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脂质组学全定量服务

产品特点:
脂质组学全定量服务脂质学(Lipidomics)的概念是随着基因组,蛋白质组研究的兴起而被提出的,最早由华人科学家韩贤林在2003提出。脂质组学是对生物体、组织或细胞中的脂质以及与其相互作用的分子进行全面系统的分析、鉴定,了解脂质的结构和功能,进而揭示脂质代谢与细胞、器官乃至机体的生理、病理过程之间的关系的一门学科。脂质分子

ZHIZHIZUGAINIAN

ZHIZHIXUE(Lipidomics)DEGAINIANSHISUIZHEJIYINZU,DANBAIZHIZUYANJIUDEXINGQIERBEITICHUDE,ZUIZAOYOUHUARENKEXUEJIAHANXIANLINZAI2003TICHU。ZHIZHIZUXUESHIDUISHENGWUTI、ZUZHIHUOXIBAOZHONGDEZHIZHIYIJIYUQIXIANGHUZUOYONGDEFENZIJINXINGQUANMIANXITONGDEFENXI、JIANDING,LEJIEZHIZHIDEJIEGOUHEGONGNENG,JINERJIESHIZHIZHIDAIXIEYUXIBAO、QIGUANNAIZHIJITIDESHENGLI、BINGLIGUOCHENGZHIJIANDEGUANXIDEYIMENXUEKE。

ZHIZHIFENZI

ZHIZHISHIZIRANJIEZHONGCUNZAIDEYIDALEIBURONGYUSHUIERYIRONGJIEYUYOUJIRONGJI、ZAIHUAXUECHENGFENJIJIEGOUSHANGFEIJUNYIDEHUAHEWU,ZHUYAOBAOKUOZHIFANGSUANJIQITIANRANFASHENGDEYANSHENGWU(RUZHIHUOAN),YIJIYUQISHENGWUHECHENGHEGONGNENGXIANGGUANDEHUAHEWU。ZHIZHINENGGOUCANYUDUOZHONGSHENGWUDAIXIE:NENGLIANGZHUANHUAN、WUZHIYUNSHU、XINXISHIBIEYUCHUANDI、XIBAOFAYUHEFENHUAJIXIBAODIAOWANGDENG。ZHIZHIDAIXIEYICHANGKEYINFAZHUDUORENLEIJIBING,BAOKUOTANGNIAOBING、FEIPANGZHENG、AIZHENGYIJISHENJINGTUIXINGXINGJIBINGDENG。MUQIAN,ZHIZHIZUXUEYIJINGBEIGUANGFANYUNYONGYUYAOWUYANFA、FENZISHENGLIXUE、FENZIBINGLIXUE、GONGNENGJIYINZUXUE、YINGYANGXUEYIJIHUANJINGYUJIANKANGDENGZHONGYAOLINGYUYANJIU。

河北快3YANJIUBIAOMINGBURUDONGWUTINEIYUECUNZAI1000-2000ZHONGZHIZHI,BINGQIESUIZHEZHIZHIYANJIUJISHUDEBUDUANFAZHAN,GEZHONGXINDEZHIZHIFENZIHAIZAIBUDUANDIBEIFAXIAN。YOUYUZHIZHIZHONGLEIFANDUO,MEIGUOGUOLIWEISHENGYANJIUYUAN(NIH)TICHUJIANGZHIZHIZHUYAOFENWEIYIXIABALEI:

脂质组学研究方法概述
1.     脂肪酸类fatty acyls

河北快32.     GANYOUZHILEIglycerolipds

河北快33.     GANYOULINZHILEIglycerophospholipids

4.     QIAOZHILEIsphingolipdis

河北快35.     GUCHUNZHILEIsterol lipids

6.     YUNXICHUNTONGZHILEIprenolipids

河北快37.     TANGZHILEIsaccharolipids

8.     DUOJUYIXILEIpolyketides

脂质组学研究方法概述
河北快3常见脂质在细胞中的分布

脂质组学研究方法概述
河北快3脂质组研究heatmap图

ZHIZHIZUXUEJIANDINGFANGFA

河北快3ZHIZHIDAIXIEWUJIEGOUJIAOWEIFUZA,ANJIXINGKEFENWEIJIXINGZHILEI(RUGANYOULINZHI、QIAOZHI)HEFEIJIXINGZHILEI(RUGANYOUZHI、DANGUCHUN)。GENJUBUTONGDEGUANNENGTUAN、TANLIANZHANGDU、SHUANGJIANSHULIANGDENGCHAYI,BUTONGDEZHIZHIYEKEZAISEPUSHANGBEIFENLI。 YIXIASHIJIZHONGCHANGYONGZHIZHIJIANDINGDEJISHUFANGFA:


河北快3“法”(shotgun method)

河北快3 JIYUDIANPENWULIZIHUAZHIPUESI-MSDE“FA”(shotgun method) SHIMUQIANYANJIUZHIZHIZUXUEZUICHANGYONGDEFENXIFANGFA。ZHIZHIYANGPINZAITICHUNHOU,BUJINGSEPUZHUFENLI,ZHIJIEJINYANGHOUGENJUZHIZHIFENZIBUTONGpHZHITIAOJIANXIADIANHECHAYIXINGJINXINGLIZIYUANNEIFENLI。ZHENG、FULIZIMOSHIXIAFENKAIJIANCEBUTONGZHIZHIFENZI。FAJUYOUYANGPINQIANCHULIJIANDAN、YANGPINYONGLIANGSHAO、FENXISHIJIANDUANDENGTEDIAN。QUEDIANSHIJIAONANFENXIDIFENGDUZHIZHI。

脂质组学研究方法概述
“法”脂质组分析实验流程

ER

QIXIANGSEPUYUZHIPULIANYONG(GC-MS)

ZHILEIXIAOFENZIDADUOJUYOUJIAOGAODEHUIFAXING,QIXIANGSEPUNENGGOUKUAISUYOUXIAODIJIANGZHIZHIYUQITADAFENZIWUZHIFENLI,ZAITONGGUOZHIPUJIANDINGZHILEIXIAOFENZI。DANDUIFENXIWUHUIFAXING、YANSHENGHUADEYAOQIUZHIYUELEGC-MSZAIZHIZHIZUXUEZHONGDEYINGYONG。

SAN

YEXIANGSEPUYUZHIPULIANYONG(LC-MS)

河北快3XIANGBIQIXIANGSEPU,YEXIANGSEPUDUIFENXIWUMEIYOUHUIFAXINGYAOQIU,YIWUXUJINXINGYANSHENGHUA,KEZAIBAOLIUZHIZHIWANZHENGXINXIDEQIANTIXIASHIXIANSEPUZHUSHANGDELIANGHAOFENLI,GUANGFANSHIYONGYUZHIZHIZUXUEYANJIU,GENJUYEXIANGSEPULIUDONGXIANGHESEPUZHULEIXINGDEBUTONG,KEFENWEIZHENGXIANGSEPU(NPLC)HEFANXIANGSEPU(RPLC)2ZHONGFENLIMOSHI。

NPLCGENJUTEZHENGGUANNENGTUANSHIXIANZHIZHILEIJIANFENLI,DANYOUYUNPLCDUOCAIYONGDENGSHUSHUIRONGXINGLIUDONGXIANG,YINCIBUYIRONGJIEJIXINGZHIZHI,DUIZHIPUJIANRONGXINGCHA,ZHIZHIDINGLIANGJIEGUOZHONGXIANXINGYEJIAODI。

RPLCGENJUZHIZHIBUBAOHEDUJITANLIANZHANGDUSHIXIANZHIZHILEINEIFENLI,DANBULIYUZHIZHILEIJIANFENLI,YOUYULIUDONGXIANGZHONGSHUIXIANGBILIJIAOGAO,FEIJIXINGZHIZHIRONGJIEXINGBUJIA,QIEQIANGJIXING、SHUIRONGXINGZHIZHIBAOLIUSHIJIANGUODUAN、FENLIDUJIAODIERXINHAODUIJIBULIYUJIANCE。

SI

QINSHUIZUOYONGSEPU-ZHIPULIANYONGJISHU(HILIC-MS)

QINSHUIZUOYONGSEPU(hydrophilic interaction liquid chromatography,HILIC)SHIYIZHONGXINXINGSEPUFENLIMOSHI,QIFENLIJIZHIJIEYUNPLCHERPLCZHIJIAN,ZHENGHELERPLCHENPLCDEYOUQUEDIAN。HILICCAIYONGWEIJIANHEGUIJIAOJIXINGGUDINGXIANGHESHUI-SHUIRONGXINGYOUJIRONGJIWEILIUDONGXIANG,YOULIYUJIXINGZHIZHIDEFENLI,KEFULENPLCHERPLCZAIJIXINGZHIZHIFENLIGUOCHENGZHONGDEBUZU,SHIZHIZHIZAILEIJIANFENLIDEJICHUSHANGJINYIBUSHIXIANLEINEIFENLI。YOUYULIUDONGXIANGHANYOUGAONONGDUYOUJIXIANG,KEZENGQIANGZHIZHILIZIHUAXIAOLV,TIGAOZHIZHIJIANCELINGMINDU,YUZHIPUYOUJIAOHAODEJIANRONGXING。

脂质组学研究方法概述
      HILIC,NPLC和RPLC几种色谱的特性比较

脂质组学研究方法概述
河北快3百泰派克生物科技依托先进高通量气相,液相色谱串联Obitrap Fusion Lumos质谱分析平台,专业统计学和生物信息学分析技术,以及经验丰富的脂质组分析专家团队,配合各类脂肪酸同位素标准品,能够对超过40 个脂肪酸进行精准定性、定量分析。关于脂质分子(组)详细实验方案和样品要求,

产品相关关键字: 脂质组学全定量服务 脂质组学全定量技术 脂质组学全定量厂家
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