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lncRNA测序服务

产品特点:
lncRNA测序服务这些类似mRNA的转录本在各种基因调控水平和胚胎发育等生物学过程中发挥作用。越来越多的证据也表明,异常表达的lncRNA在多种疾病状态中发挥重要作用,如癌症。这些RNA尽管在十几年前就已经发现,但只有少数分子的功能得到鉴定。

河北快3RENSHENGRUXI,XIANGXINZHANGLIANFEIBIANMARNA(lncRNA)YETIHUIDAOLE。ZHIQIANYIZHIZAOLENGYU,RUJINQUESHIWANRENMI。QISHI,RENLEIJIQITABURUDONGWUDEJIYINZUZHUANLULESHUWANTIAOlncRNA。GENJUGenCodeSHUJUKUZHONGBANBENDESHUJU,RENLEIJIYINZUZHONGBAOHAN16,000TIAOlncRNA,CHANSHENGLEJIN28,000TIAOZHUANLUBEN。ZAIJIASHANGQITASHUJUKUDESHUJU,MUQIANYIZHIDElncRNACHAOGUO40,000TIAO。

河北快3ZHEIXIELEISImRNADEZHUANLUBENZAIGEZHONGJIYINDIAOKONGSHUIPINGHEPEITAIFAYUDENGSHENGWUXUEGUOCHENGZHONGFAHUIZUOYONG。YUELAIYUEDUODEZHENGJUYEBIAOMING,YICHANGBIAODADElncRNAZAIDUOZHONGJIBINGZHUANGTAIZHONGFAHUIZHONGYAOZUOYONG,RUAIZHENG。ZHEIXIERNAJINGUANZAISHIJINIANQIANJIUYIJINGFAXIAN,DANZHIYOUSHAOSHUFENZIDEGONGNENGDEDAOJIANDING。

河北快3DEKESASIDAXUEXINANYIXUEZHONGXINDEYAOLIXUEJIAOSHOUDavid CoreyBIAOSHI:“NIBIXUCONGJIANCEFEIBIANMAZHUANLUBENKAISHI。”TADEYANJIUFANGXIANGSHIJIANGlncRNAZUOWEIYAOWUBADIAN。“WODUIZHEIXIESHUJUKUBUGANMAO,YINWEIKENENGCUNZAICUOWU。TAMENKENENGJIANCEDAONIDEXIBAOXIZHONGBUCUNZAIDERNAHUOHENSHAOLIANGDERNA。”

RUOBINGFEIQUANJIYINZUFANWEINEIDEJIANCE,CoreyBOSHITONGCHANGLIYONGDINGLIANGPCRLAIJIANCEFEIBIANMAZHUANLUBEN。“RUGUOWOMENRENWEINEIERYOUYITIAOFEIBIANMAZHUANLUBEN,WOMENJIUYONG5’HE3’ RACELAIKUOZENGHEJIANCEZHEIXIEQUYU,”TASHUO。“LEJIETADEQISHIWEIDIANHEZHONGZHIWEIDIANSHIJIANHAOSHI,DANBUYIDINGSHIBIXUDE。RUGUONIZHUYAODUIGONGNENGGANXINGQU,NEIMEJIUBUYONGLEJIEQUANBUQINGKUANG,RUOCUNZAIZHONGDIEDEZHUANLUBEN,JIANCEQILAIYEBIJIAOKUNNAN。”

RUGUOZHUANLUBENDEQUECUNZAI,XIAYIBUZESHILIYONGNIZHUANLULAISHENGCHENGRNA,“HUOZHEGOUMAIYITIAOSHIDANGZHANGDUDERNA,DANSHIXULIEBIXUXIANGTONG,”CoreyBOSHISHUO。“NIBIXUSHIYONGWANQUANXIANGTONGDEqPCRYINWU,FOUZESHIZHIHAOLI,MIUYIQIANLI。”

河北快3DANGRAN,YUmRNAXIANGBI,FENXIZHEIXIElncRNAMIANLINDUTEDETIAOZHAN。JUArrayStarDEZISHENKEXUEJIAYanggu ShiJIESHAO,lncRNADEFENGDUSHUIPINGTONGCHANGBImRNADISHIBEI,ERQIEZUZHITEYIXINGGAO,JIN80%DElncRNASHIZUZHITEYIDE,DANmRNABUDAO20%。lncRNADEZHUSHIBIJIAOSHAO,YINWEITAMENBUBIANMADANBAIZHI。CIWAI,YIXIElncRNAMEIYOUpoly(A)WEI。TAMENDADUOWEIYUXIBAOHEZHONG。“JIYUZHEIXIEYUANYIN,WOMENXUYAOYIXIETESHUFANGFALAIFENXIHEZHUSHI,”ShiBOSHISHUO。ArrayStarZHUANMENKAIFAFENXIRNABIAODAHEDIAOKONGDEGONGJU,TEBIESHIDIAOKONGXINGDEFEIBIANMARNA。

河北快3JUGELIZI,RNACEXUTONGCHANGCHANSHENG4000WANTIAOXULIE,DANlncRNADECEXUFUGAIDUTAIDI,BUZUYIJINXINGKEKAODINGLIANG。“LIYONGZHEIZHONGFANGFA,lncRNACEXUZHISHAOXUYAO1YITIAOXULIE,BICHANGGUIDEmRNACEXUYAODUODEDUO,”ShiBOSHIJIESHIDAO。“XIANGBIZHIXIA,XINPIANSHOUDIFENGDUZHUANLUBENDEYINGXIANGMEINEIMEDA,QIECUOWUDINGLIANGDEJILVJIAODI。”

JUShiBOSHIJIESHAO,ArrayStarDElncRNAXINPIANDAIYOUXUDUOZHUSHI,DEDAOSHIYANZHICHI,BINGBEIXUDUOWENXIANYINYONG。BIRU,ArrayStarXINPIANCENGCHUXIANZAI《Nature Cell Biology》DEYIPIANLUNWENZHONG,SHUOMINGSANYINRUXIANAIZHONGDEXIBAOZHILINK-A lncRNAJIHUOLECHANGYANGXIADEHIF1αXINHAOTONGLU1。

产品相关关键字: lncRNA测序服务 lncRNA测序服务 lncRNA测序服务
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